Aorta
Occlusive disease

Acute limb ischemia on graft thrombosis and severe pancreatitis

Management of acute limb graft thrombosis can be challenging, especially for an obese patient with Balthazar E severe pancreatitis and ARDS...

Hospital: Paris Saint-Joseph, France
Part I - Case presentation

A 64-year-old female patient was referred for Rutherford IIB acute leg ischemia due to limb graft thrombosis, complicating a severe Balthazar E pancreatitis with respiratory distress. 

Previous medical history included EVAR for AAA two years ago. She was stated ASA 4 by the anesthesiologist team due to her medical condition and risk factors (Obesity BMI 35; diabetes).

Video 1: Angio CT scan showing left leg thrombosis

Powered by Quiz Maker

 

Part II - Treatment

Due to her respiratory condition, anesthesiologists were reluctant to perform general anesthesia and mechanical ventilation.

Furthermore, hostile groins (obesity, previous open access, infectious risk) were good arguments for a percutaneous approach under local anesthesia.

As thrombus extended into CFA, a 7 Fr sheath was place via a retrograde ultrasound-guided puncture of the SFA. 

Penumbra Lightning™ 7 Fr device was used to remove thrombus inside the graft. 

After thrombus removal, a completion angio highlighted a proximal limb stenosis treated by placement of a covered stent (Bentley BeGratf 10 x 57 mm, then over inflated with a 12 mm balloon) (videos 2 and 3).

Video 2: Thrombus removal using Penumbra Lightning™ 7 Fr
Video 3: Angio after stenting proximal part of graft limb

Second angio (video 4) showed persistant low flow in the SFA and proximal occlusion of PFA due to residual thrombus.

After complete removal using Penumbra, a normal blood flow was restored (video 5).
 

Video 4: Low flow in SFA due to residual thrombus
Video 5: Final angio

Arterial access was closed using a 6 F Angioseal

Then, patient was transferred to ICU and underwent several abdominal surgeries following her pancreatitis (necrosis removal, colectomy with temporary abdominal closure for second look).